Primary glioblastoma multiforme of the conus medullaris with leptomeningeal metastasis

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منابع مشابه

Glioblastoma multiforme in the adult conus medullaris.

De novo glioblastoma multiforme (GBM) of the spine is rare. We present a patient with a unique GBM arising within the conus and radiographically mimicking a filum terminale ependymoma. During surgery the lesion was notable for its highly vascular and diffuse infiltration of the surrounding spinal cord parenchyma. The operative goals were altered to account for the unexpected pathology. The trea...

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Glioblastoma multiforme in conus medullaris with intracranial metastasis after postoperative adjuvant therapy

Spinal glioblastoma multiforme is not common among spinal cord tumors. According to our literature review, only 27 cases originating from the conus medullaris were reported. We herein reported a case of a 10-year-old child diagnosed with glioblastoma multiforme. The patient received adjuvant radiotherapy and standard temozolomide chemotherapy after total excision. Intracranial lesions were foun...

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Glioblastoma multiforme intraxial metastasis to the conus medullaris with primary disease under control: a rare unexpected finding.

We report on glioblastoma multiple spinal intraaxial metastases with primary disease radiologically under control. The case highlights glioblastoma biological behavior and spread mechanisms; dissemination may have occurred initially and been controlled by chemotherapy, or more likely, is an indicator that even if radiologically dormant, disease is unlikely biologically inactive.

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Glioblastoma multiforme of the conus medullaris in a child: description of a case and literature review.

We describe a case of glioblastoma multiforme of the conus medullaris in a child. MR imaging showed at the T12-L1 level an intramedullary mass with signal alteration, with only two nodules of contrast enhancement. The finding was consistent with astrocytoma. Pathologic evaluation was consistent with glioblastoma multiforme. Nine months after the surgical treatment, the patient showed leptomenin...

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Spinal cord glioblastoma multiforme of conus medullaris masquerading as high lumbar disk herniation.

BACKGROUND A case of primary intramedullary glioblastoma occurring at conus medullaris is presented, which was initially undetected and misdiagnosed as L1 through L2 disk herniation. CASE DESCRIPTION After the performance of L1 through L2 discectomy, the patient's initial painful symptom did not subside. The patient then developed a progressive paraparesis. The outside surgeons only predicted...

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ژورنال

عنوان ژورنال: Journal of the Neurological Sciences

سال: 2017

ISSN: 0022-510X

DOI: 10.1016/j.jns.2017.09.004